The epic adventure-romance film has been directed by Ashutosh Gowariker and also stars Hrithik Roshan.
In the picture Pooja is seen in a regal avatar decked in a bejewelled head gear and a blue and red outfit.
"CHAANI,The Chosen One of Mohenjo Daro @iHrithik @agppl_tweets @utvfilms @arrahman #Epic #MohenjoDaro #Chaani," Pooja wrote alongside the picture.
Pooja has earlier starred in Tamil superhero film "Mugamoodi" in 2012, Telugu films "Oka Laila Kosam" and "Mukunda" in 2014.
"Mohenjo Daro" is set in the ancient city of Mohenjo-daro in the era of the Indus Valley civilisation that dates back to 2600 BC. It is slated for release on August 12.