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This gene could reduce inflammation after stroke

Researchers have found that a gene could help the brain heal itself after a stroke or any other head-related injuries.

The study, published in Cell Reports, suggested that a dose of the TRIM9 gene could reduce brain swelling after stroke, prevent damage following a blow to the head (concussion) or encephalitis, which is the inflammation of the brain.

In addition, in a lab model, the researchers from the University of Southern California found that older brains with low TRIM9 levels – or engineered brains missing the TRIM9 gene entirely – were prone to extensive swelling following a stroke. On the other hand, when the team used a harmless virus to carry a dose of the gene directly into TRIM9-deficient brains, the swelling decreased dramatically and recovery improved, the findings further revealed.

However, inflammation for a long duration could lead to the death of neurons.

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