Europa League: Manchester United lose in Denmark

Manchester United's Europa League campaign resumed with a defeat in Denmark as Midtjylland prevailed 2-1 in the first leg of the round of 32.

The result might have been worse if not for a few fine saves by Sergio Romero, who made his first appearance for United since October after David De Gea suffered an injury in the warm-up.

Romero had made two good saves before United took the lead on 37 minutes. Memphis Depay stretched to knock down a Jesse Lingard cross, then managed to shoot the ball over the line while off-balance.

But United were denied a half-time lead as Pione Sisto showed good speed with the ball at the top of the box before putting a shot past Romero with a slight deflection of Chris Smalling.

Romero made another fine save after the hour mark to deny Paul Onuachu and keep the game level with a diving effort. But he could not prevent Onuachu from giving Midtjylland the lead in the 77th minute.

The 6-foot-7 substitute shrugged off a challenge at the top of the box from Juan Mata, who stands a full foot shorter than the Nigerian, and fired a low shot that crept inside the post.

Tottenham held on for a 1-1 draw with Fiorentina after initially taking the lead in Italy.

Spurs led in the 37th minute after Ben Davies was fouled in the box and Nacer Chadli converted the penalty.

But the Serie A side were back level when Federico Bernardeschi took a shot from 30 yards that took a big deflection off the boot of Ryan Mason and looped over Michel Vorm.

Fiorentina kept up the pressure in search of a winner, but Tottenham will enjoy a slim away-goals advantage for next week's return leg.

Lukasz Piszczek and Marco Reus scored to help Borussia Dortmund defeat Porto 2-0 at home.

Poland international Piszczek headed home following a corner in the sixth minute for his first goal in the competition since 2009.

Henrikh Mkhitaryan pulled the ball back for  Reus to add a second goal after the break.

Former Dortmund boss Jurgen Klopp had no joy in his return to Germany as his Liverpool side were held to a goalless draw at Augsburg.

Denis Suarez scored on a sharp free kick to give Villarreal a 1-0 victory at home over Italian contenders Napoli in their home leg.

Valencia ran riot in their home leg against Rapid Vienna, winning 6-0 with five of their goals coming in the opening 35 minutes.