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‘Bird flu likely mutated within Louisiana patient’

Washington: A genetic analysis suggests the bird flu virus mutated inside a Louisiana patient who contracted the nation’s first severe case of the illness, the US Centres for Disease Control and Prevention said this week.

Scientists believe the mutations may allow the virus to better bind to receptors in the upper airways of humans — something they say is concerning but not a cause for alarm.

Michael Osterholm, a University of Minnesota infectious disease researcher, likened this binding interaction to a lock and key. To enter a cell, the virus needs to have a key that turns the lock, and this finding means the virus may be changing to have a key that might work. “Is this an indication that we may be closer to seeing a readily transmitted virus between people? No,” Osterholm said. “Right now, this is a key that sits in the lock, but it doesn’t open the door.”

The virus has been causing sporadic, mostly mild illnesses in people in the US, and nearly all of those infected worked on dairy or poultry farms.

The Louisiana patient was hospitalized in critical condition with severe respiratory symptoms from bird flu after coming in contact with sick and dead birds in a

backyard flock.

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