A new COVID-19 challenge: Mutations rise along with cases

A new COVID-19 challenge: Mutations rise along with cases

Washington DC: The race against the virus that causes COVID-19 has taken a new turn: Mutations are rapidly popping up, and the longer it takes to vaccinate people, the more likely it is that a variant that can elude current tests, treatments and vaccines could emerge.

The Coronavirus is becoming more genetically diverse, and health officials say the high rate of new cases is the main reason. Each new infection gives the virus a chance to mutate as it makes copies of itself, threatening to undo the progress made so far to control the pandemic.

On Friday, the World Health Organisation urged more effort to detect new variants. The US Centres for Disease Control and Prevention said a new version first identified in the United Kingdom may become dominant in the US by March.

Although it doesn't cause more severe illness, it will lead to more hospitalisations and deaths just because it spreads much more easily, said the CDC, warning of a new phase of exponential growth .

"We're taking it really very seriously," Dr Anthony Fauci, the US government's top infectious disease expert, said Sunday on NBC's Meet the Press.

"We need to do everything we can get transmission as low as we possibly can," said Harvard University's Dr Michael Mina. The best way to prevent mutant strains from emerging is to slow transmission.

So far, vaccines seem to remain effective, but there are signs that some of the new mutations may undermine tests for the virus and reduce the effectiveness of antibody drugs as treatments.

We're in a race against time" because the virus may stumble upon a mutation that makes it more dangerous, said Dr Pardis Sabeti, an evolutionary biologist at the Broad Institute of MIT and Harvard.

Younger people may be less willing to wear masks, shun crowds and take other steps to avoid infection because the current strain doesn't seem to make them very sick, but in one mutational change, it might, she warned. Sabeti documented a change in the Ebola virus during the 2014 outbreak that made it much worse.

It's normal for viruses to acquire small changes or mutations in their genetic alphabet as they reproduce. Ones that help the virus flourish give it a competitive advantage and thus crowd out other


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