New Delhi: UK-based pharmaceutical major AstraZeneca has started global withdrawal of its Covid-19 vaccine, which was provided in India as ‘Covishield’ in partnership with Serum Institute of India, days after it admitted to rare side-effects of blood clotting and lowering of platelet counts.
The withdrawal has been initiated due to a surplus of available updated vaccines since the pandemic, the company said in a statement. In India, the company’s partner Serum Institute of India (SII) said it has stopped the manufacturing and supply of additional doses of Covishield since December 2021 while reiterating that it had disclosed all rare to very rare side-effects, including Thrombosis with Thrombocytopenia Syndrome, in the packaging insert in 2021.
AstraZeneca had partnered with Oxford University to develop the Covid-19 vaccine, which was sold in India as Covishield and as Vaxzevria in Europe.
“As multiple, variant Covid-19 vaccines have since been developed there is a surplus of available updated vaccines. This has led to a decline in demand for Vaxzervria, which is no longer being manufactured or supplied,” AstraZeneca said.
The company further said, “We will now work with regulators and our partners to align on a clear path forward to conclude this chapter and significant contribution to the Covid-19 pandemic.” Earlier, according to global media reports, AstraZeneca had admitted that its Covid-19 vaccine could in very rare cases has the potential to cause a rare side-effect called Thrombosis with Thrombocytopenia Syndrome (TTS).
Without referring to the side-effects, the company said, “We are incredibly proud of the role Vaxzevria played in ending the global pandemic. According to independent estimates, over 6.5 million lives were saved in the first year of use alone and over three billion doses were supplied globally.”
It further said, “Our efforts have been recognised by governments around the world and are widely regarded as being a critical component of ending the global pandemic.”
The European Medicines Agency, the medicines regulator for the European Union (EU), issued a notice on Tuesday to confirm that Vaxzevria -- known as Covishield in India -- is no longer authorised for use in the 27-member economic bloc after AstraZeneca voluntarily withdrew its authorisation in March.