The 73-year-old actor is ahead of superstars like Shah Rukh Khan (20.8 million), Salman Khan (19 million), Aamir Khan (18.3 million), and Bollywood stars Deepika Padukone and Priyanka Chopra, who have 15.6 million and 14.8 million followers respectively.
Bachchan, who joined Twitter in 2010, expressed his excitement through a post and shared the news along with a picture of himself in which he is seen joining hands and greeting his followers for all the love.
"BAAADUUUUMMMBAAAA! Twitter followers reaches 22 million #AB22Million.. Thank you all.. Your love made it," wrote the actor.
From sharing posters, behind-the-scene stills of his movies, trivia of his old films to voicing his opinion on a range of issues, Bachchan is quite active on Twitter.
The National Award-winning actor is also active on other social media platforms, Facebook and blog.